Microwave-assisted Multi-component Reaction for the Green Synthesis of Novel 4-(5-hydroxybenzo[a]phenazin-6-yl)-5-phenyl-1, 3-dihydro-2H-imidazol-2-one Using H₃PW₁₂O₄₀@nano-TiO₂ as Recyclable Catalyst

In this context, we have demonstrated a highly efficient and green process for the preparation of various potentially biologically active functionalized 4-(5-hydroxybenzo[a]phenazin-6-yl)-5-phenyl-1,3-dihydro-2H-imidazol-2-one derivatives via one-pot, four-component cyclo-condensation reaction in presence catalytic amounts phosphotungstic acid supported on TiO2 as nontoxic, reactive, eco-friendly solid catalyst under MWI solvent-free conditions. The crystallinity crystallite size nano-TiO2 were fabricated characterized by X-ray diffraction (XRD), Transmission electron microscopy (TEM), scanning (FESEM), Thermogravimetric Analysis (TGA), Fourier transform infrared (FT-IR), Brunauer-Emmett-Teller (BET), atomic force (AFM). We believe that work can provide new insights into fabrication high-performance photocatalysts facilitate their practical application environmental issues.